IsobaricQuantifier.h

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//                   OpenMS -- Open-Source Mass Spectrometry
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// Copyright The OpenMS Team -- Eberhard Karls University Tuebingen,
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// $Maintainer: Timo Sachsenberg $
// $Authors: Stephan Aiche, Chris Bielow $
// --------------------------------------------------------------------------
 
#pragma once
 
#include <OpenMS/DATASTRUCTURES/DefaultParamHandler.h>
#include <OpenMS/ANALYSIS/QUANTITATION/IsobaricQuantifierStatistics.h>
 
namespace OpenMS
{
  class IsobaricQuantitationMethod;
  class ConsensusMap;
 
  class OPENMS_DLLAPI IsobaricQuantifier :
    public DefaultParamHandler
  {
public:
    explicit IsobaricQuantifier(const IsobaricQuantitationMethod* const quant_method);
 
    IsobaricQuantifier(const IsobaricQuantifier& other);
 
    IsobaricQuantifier& operator=(const IsobaricQuantifier& rhs);
 
    void quantify(const ConsensusMap& consensus_map_in, ConsensusMap& consensus_map_out);
 
protected:
    void setDefaultParams_();
 
    void updateMembers_() override;
 
private:
    IsobaricQuantifierStatistics stats_;
 
    const IsobaricQuantitationMethod* quant_method_;
 
    bool isotope_correction_enabled_;
 
    bool normalization_enabled_;
 
    void computeLabelingStatistics_(ConsensusMap& consensus_map_out);
  };
} // namespace